1.What Kava Kava Extract Powder ?
Kava Kava Extract Powder (also known as Kava, Piper methysticum) is an herb that has been used in rituals for a long time in Oceania. The traditional drink is made by soaking kava roots in cold water. Ingestion of kava usually produces unique relaxing effects without intoxication or hallucinations, but excessive consumption can cause vomiting and head pain. In Oceania, the traditional use of this plant is prevalent and continues to this day.
2. The health benefits of Piper Methysticum Extract
▲Anti-anxiety effect
Kava Kava Extract Powder contain a compound called kavalactone. While we do not currently fully understand it, kava appears to have several activities that contribute to relaxation.
Like other traditionally calming nerve substances (including valerian, passionflower, lavender, and lemon balm), kava also has an effect on the gamma-aminobutyric acid (GABA) neurotransmitter. GABA is the main controlling neurotransmitter in the central nervous system and slows down brain activity. Although kava piperonide binds weakly to GABA receptors, it appears to greatly enhance binding to other molecules. By strengthening the binding of these molecules, kava piperonolide enhances GABA activity.
However, kava differs from other common neurosedatives in that it also has a strong effect on voltage-gated sodium channels (VGSC). VGSCs are channels in the cell membrane that are important for general neural function. When sodium channels open, electrical signals travel along the nerve, creating nerve impulses. Kavakolide appears to block sodium channels, which reduces overall brain and nerve activity. This effect, combined with the effect of enhancing the binding of the molecule to GABA receptors, may be the reason for the anti-anxiety effects of kava preparations.
▲Relieve inflammation and anticoagulant effect
As early as the 1960s, animal studies began to show that this herb had a significant effect on reducing inflammation. This study shows that kava Extract can reduce the inflammatory response caused by exposure to a large number of compounds and UV light.
Tumor necrosis factor- (TNF- ) is a major inflammatory cell signaling molecule. Standard drug fixes for some autoimmune diseases include control of TNF-alpha. Several kava lactones contained in kava appear to control TNF-alpha. Endotoxin is a compound present in the outer membrane of Gram-negative bacteria that can strongly induce an inflammatory response. After giving mice a lethal dose of endotoxin, kava was able to immunize the mice against an inflammatory response that would normally be fatal.
These anti-inflammatory effects also appear to reduce inflammatory-induced coagulation events. This effect appears to work by controlling the inflammatory response pathway mediated by arachidonic acid, a pro-inflammatory fat.
▲Sleep support
Substances that relieve anxiety often also help with insomnia, and vice versa. There are exceptions though, like melatonin is only used for sleep, but most natural remedies for anxiety and insomnia are interchangeable to some extent. Standard drug for inducing sleep and commonly prescribed by doctors for anxiety.
Therefore, it should come as no surprise that some clinical trials have found that kavaExtract can help optimize insomnia. A pilot study exploring the effects of Kava and valerian for stress-induced insomnia found that both treatments were helpful. Both kava and valerian reduce stress and insomnia.
A double-blind placebo-controlled trial evaluated the efficacy of kava on anxiety-related sleep disturbances. The researchers found that kava optimized sleep and reduced anxiety over the four weeks of the study. A large internet-based study found that kava was not significantly better than a placebo in repairing insomnia, although that was also because the placebo had a significant effect. Both kava and placebo reduced insomnia severity scores by nearly half.
More research is needed to multi-facetedly assess the effects of kava on insomnia. However, given that the anxiety-reducing properties of kava are well established in published studies, it appears that kava has the potential to alleviate some symptoms, at least for some people with sleep disorders.
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